The Best Severe Cold And Flu – 2022

After hours of researching and comparing all models on the market, we find out the Best Severe Cold And Flu of 2022. Check our ranking below.

Our Picks For The Top Severe Cold And Flu

Overall Product Rankings

Rank No. 1
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
  • 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the #1 doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
  • The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
  • The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
  • Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
  • The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.
Rank No. 2
Amazon Basic Care Nighttime Severe Vapor Ice Cold and Flu, Coated Caplets, Temporarily relieves Common Cold and flu Symptoms Like runny Nose and Sneezing
  • ACTIVE INGREDIENTS: This product contains a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant. Compare to the active ingredients in Vicks NyQuil Severe+ VapoCOOL
  • EFFECTIVE: Temporarily relieves common cold and flu symptoms such as nasal congestion, sinus congestion and pressure, runny nose and sneezing, minor aches and pain, sore throat and cough
  • COATED CAPLETS provide maximum strength, common cold and flu symptom relief
  • NIGHTTIME COLD and FLU RELIEF for minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
  • VAPOR ICE: Soothing Vapor Ice flavor in gluten free cold and flu symptom medicine
Rank No. 3
Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Combination Pack, Liquid Medicine, Packaging May Vary, 24 Fluid Ounces
  • ACTIVE INGREDIENTS: Compare this daytime and nighttime cold medicine to Vicks DayQuil Severe and Vicks NyQuil Severe active ingredients
  • DAYTIME RELIEF: Daytime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant) and phenylephrine HCl (nasal decongestant) to help you power through the day
  • NIGHTTIME RELIEF: Nighttime Severe cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), doxylamine succinate (antihistamine) and phenylephrine HCl (nasal decongestant) so you can rest at night
  • AROUND THE CLOCK: Relieve symptoms during the day and at night while you sleep with Amazon Basic Care Daytime and Nighttime Severe Cold and Flu Relief
  • MAXIMUM STRENGTH: Get maximum strength relief for your severe cold and flu symptoms
Rank No. 4
Maximum Strength Mucinex Fast-Max Day Cold & Flu & Nightshift Night Severe Cold & Flu All In One, Fast Release, Powerful Multi-Symptom Relief, 40 caplets (24 Day time + 16 Night time)
  • MAXIMUM STRENGTH MUCINEX FAST-MAX DAY COLD and FLU and NIGHTSHIFT NIGHT SEVERE COLD and FLU: Fast Release, Powerful Multi-Symptom Relief medicine. 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine
  • DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal and sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat
  • NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Nightshift Severe Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose, sore and itchy throat and allergy symptoms
  • No.1 TRUSTED COLD and COUGH BRAND: No.1 Cold and Cough brand doctors trust for themselves and their families and No.1 Pharmacist Recommended Expectorant
  • DAY TIME ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen - Pain reliever; Dextromethorphan HBr - Cough Suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal Decongestant
  • NIGHT TIME ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen - Pain reliever and Fever reducer; Dextromethorphan HBr - Cough Suppressant; Phenylephrine HCI - Nasal Decongestant; Triprolidine HCI - Antihistamine
Rank No. 6
Vicks DayQuil & NyQuil Severe Honey, Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, Day & Night Relief, 12 FL Day & Night Pack
  • MAX STRENGTH MULTI-SYMPTOM RELIEF. Relieves cough, headache, fever, sore throat, minor aches & pains, nasal congestion, sinus pressure, fever, sneezing & runny nose
  • Great Tasting
  • COATS AND SOOTHES. DayQuil and NyQuil SEVERE Honey coat your throat and also help to soothe soreness and irritation
  • FEEL BETTER FAST. Life doesn't stop when you have a cold. DayQuil Severe Honey fights your worst cold and flu symptoms so you can power through your day
  • POWERFUL RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. NyQuil Severe Honey fights your worst cold and flu symptoms so you can rest
Rank No. 7
Theraflu Multi-Symptom Severe Cold and Theraflu Nighttime Severe Cold and Cough Hot Liquid Powder Combo Pack 12 count Box
  • Includes our most popular daytime and nighttime hot liquids formulas - Theraflu Multi-Symptom Severe Cold and Theraflu Nighttime Severe Cold and Cough Hot Liquid Powder Combo Pack to treat your symptoms during day and night
  • The hot liquid provides a soothing effect. Perfect for day or night
  • For adults and children 12 years of age and over. Tackles your worst cold, flu and cough symptoms
  • Theraflu Multi-Symptom Severe Cold comes in refreshing green tea and honey lemon flavors
  • Theraflu Nighttime Severe Cold and Cough comes in soothing honey lemon, chamomile, and white tea flavors
  • Both can be taken every 4 hours, while symptoms persist. Do not take more than 5 packets in 24 hours unless directed by a doctor
  • Theraflu Multi-Symptom Severe Cold formula contains Acetaminophen 500 mg, Dextromethorphan HBr 20 mg, and Phenylephrine HCI 10 mg
  • Theraflu Nighttime Severe Cold and Cough formula contains Acetaminophen 650 mg, Diphenhydramine HCl 25 mg, and Phenylephrine HCI 10 mg
  • HSA and FSA eligible product
Rank No. 8
Rite Aid Severe Flu and Cold Relief Caplets - 24 Count | Pain Relief | Congestion Relief | Fever Reducer | Sinus Medicine for Adults | Decongestants for Adults | Cold and Flu Medicine for Adults
  • MULTI-SYMPTOM RELIEF: You’ll feel relief from headache, fever, sore throat, nasal congestion, cough, mucus, and chest congestion with Rite Aid. Compare Rite Aid Pharmacy’s Severe Cold & Flu caplets to the active ingredients in top national brands.
  • FOR YOUR SEVERE SYMPTOMS: With Rite Aid Severe Cold & Flu sinus medicine for adults, you’ll get a pain reliever/fever reducer, cough suppressant to calm your cough, expectorant to power through mucus, and nasal decongestants for adults for congestion.
  • FEVER & PAIN RELIEVER: 325mg of Acetaminophen in each caplet temporarily relieves common cold symptoms like minor aches and pains, headache, sore throat and fever. While our cough suppressant and nasal decongestant clear your cough and congestion.
  • COOL BLAST: You’ll know it’s working when you feel the cool blast flavor. Rite Aid’s Severe Cold & Flu has Acetaminophen 325mg; cough suppressant, Dextromethorphan HBr 10mg; expectorant, Guaifenesin 200mg; and nasal decongestant, Phenylephrine HCI 5mg.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
Rank No. 9
GoodSense Vapor Ice Daytime and Nighttime Severe Cold and Flu, Coated Caplets, Combo Pack, 24 Count
  • ACTIVE INGREDIENTS: GoodSense Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
  • EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
  • COMBINATION PACK: GoodSense Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
  • COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
  • MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with GoodSense Vapor Ice Daytime and Nighttime Severe Cold and Flu
Rank No. 10
Vicks DayQuil & NyQuil LiquiCaps, Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, Day & Night Relief, 72 LiquiCaps (48 DayQuil, 24 NyQuil)
  • Powerful cold symptom relief, day or night. Get powerful 6-symptom relief with DayQuil/NyQuil LiquiCaps
  • Dayquil non-drowsy, multi-symptom daytime relief. Temporarily relieves common cold & Flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
  • Nyquil nighttime relief. Temporarily relieves common cold & Flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and Pains, fever, runny nose and sneezing so you can sleep
  • #1 Pharmacist recommended over-the-counter cold & Cough medicine from Vicks, the world’s #1 Selling cough & Cold brand
  • Multi-symptom relief with NyQuil Cold & Flu, which also contains a nasal decongestant and DayQuil cold & Flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive

How Do You Buy The Best Severe Cold And Flu?

Do you get stressed out thinking about shopping for a great Severe Cold And Flu? Do doubts keep creeping into your mind? We understand because we’ve already gone through the whole process of researching Severe Cold And Flu, which is why we have assembled a comprehensive list of the greatest Severe Cold And Flu available in the current market. We’ve also come up with a list of questions that you probably have yourself.

We’ve done the best we can with our thoughts and recommendations, but it’s still crucial that you do thorough research on your own for Severe Cold And Flu that you consider buying. Your questions might include the following:

  • Is it worth buying an Severe Cold And Flu?
  • What benefits are there with buying an Severe Cold And Flu?
  • What factors deserve consideration when shopping for an effective Severe Cold And Flu?
  • Why is it crucial to invest in any Severe Cold And Flu, much less the best one?
  • Which Severe Cold And Flu are good in the current market?
  • Where can you find information like this about Severe Cold And Flu?

We’re convinced that you likely have far more questions than just these regarding Severe Cold And Flu, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.

Potential sources can include buying guides for Severe Cold And Flu, rating websites, word-of-mouth testimonials, online forums, and product reviews. Thorough and mindful research is crucial to making sure you get your hands on the best possible Severe Cold And Flu. Make sure that you are only using trustworthy and credible websites and sources.

We provide an Severe Cold And Flu buying guide, and the information is totally objective and authentic. We employ both AI and big data in proofreading the collected information. How did we create this buying guide? We did it using a custom-created selection of algorithms that lets us manifest a top-10 list of the best available Severe Cold And Flu currently available on the market.

This technology we use to assemble our list depends on a variety of factors, including but not limited to the following:

  1. Brand Value: Every brand of Severe Cold And Flu has a value all its own. Most brands offer some sort of unique selling proposition that’s supposed to bring something different to the table than their competitors.
  2. Features: What bells and whistles matter for an Severe Cold And Flu?
  3. Specifications: How powerful they are can be measured.
  4. Product Value: This simply is how much bang for the buck you get from your Severe Cold And Flu.
  5. Customer Ratings: Number ratings grade Severe Cold And Flu objectively.
  6. Customer Reviews: Closely related to ratings, these paragraphs give you first-hand and detailed information from real-world users about their Severe Cold And Flu.
  7. Product Quality: You don’t always get what you pay for with an Severe Cold And Flu, sometimes less, and sometimes more.
  8. Product Reliability: How sturdy and durable an Severe Cold And Flu is should be an indication of how long it will work out for you.

We always remember that maintaining Severe Cold And Flu information to stay current is a top priority, which is why we are constantly updating our websites. Learn more about us using online sources.

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